Grupa A
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Arsenal FC | 6 | 5 | 0 | 1 | 8 | 3 | 5 | 15 |
| 2 | PSV Eindhoven | 6 | 4 | 1 | 1 | 15 | 4 | 11 | 13 |
| 3 | FK Bodø/Glimt | 6 | 1 | 1 | 4 | 5 | 10 | -5 | 4 |
| 4 | FC Zürich | 6 | 1 | 0 | 5 | 5 | 16 | -11 | 3 |
Meciuri
8.09.2022, 19:45
FC Zürich – Arsenal FC
1 – 2
8.09.2022, 19:45
PSV Eindhoven – FK Bodø/Glimt
1 – 1
15.09.2022, 22:00
FK Bodø/Glimt – FC Zürich
2 – 1
6.10.2022, 19:45
FC Zürich – PSV Eindhoven
1 – 5
6.10.2022, 22:00
Arsenal FC – FK Bodø/Glimt
3 – 0
13.10.2022, 19:45
FK Bodø/Glimt – Arsenal FC
0 – 1
13.10.2022, 22:00
PSV Eindhoven – FC Zürich
5 – 0
20.10.2022, 20:00
Arsenal FC – PSV Eindhoven
1 – 0
27.10, 2022, 19:45
PSV Eindhoven – Arsenal FC
2 – 0
27.10, 2022, 19:45
FC Zürich – FK Bodø/Glimt
2 – 1
3.11.2022, 22:00
Arsenal FC – FC Zürich
1 – 0
3.11.2022, 22:00
FK Bodø/Glimt – PSV Eindhoven
1 – 2
Grupa B
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Fenerbahçe SK | 6 | 4 | 2 | 0 | 13 | 7 | 6 | 14 |
| 2 | Stade Rennais FC | 6 | 3 | 3 | 0 | 11 | 8 | 3 | 12 |
| 3 | AEK Larnaca FC | 6 | 1 | 2 | 3 | 7 | 10 | -3 | 5 |
| 4 | FC Dinamo Kiev | 6 | 0 | 1 | 5 | 5 | 11 | -6 | 1 |
Meciuri
8.09.2022, 19:45
Fenerbahçe SK – FC Dinamo Kiev
2 – 1
8.09.2022, 19:45
AEK Larnaca FC – Stade Rennais FC
1 – 2
15.09.2022, 22:00
FC Dinamo Kiev – AEK Larnaca FC
0 – 1
15.09.2022, 22:00
Stade Rennais FC – Fenerbahçe SK
2 – 2
6.10.2022, 22:00
Stade Rennais FC – FC Dinamo Kiev
2 – 1
6.10.2022, 22:00
Fenerbahçe SK – AEK Larnaca FC
2 – 0
13.10.2022, 19:45
FC Dinamo Kiev – Stade Rennais FC
0 – 1
13.10.2022, 19:45
AEK Larnaca FC – Fenerbahçe SK
1 – 2
27.10.2022, 19:45
AEK Larnaca FC – FC Dinamo Kiev
3 – 3
27.10.2022, 19:45
Fenerbahçe SK – Stade Rennais FC
3 – 3
3.12.2022, 22:00
FC Dinamo Kiev – Fenerbahçe SK
0 – 2
3.12.2022, 22:00
Stade Rennais FC – AEK Larnaca FC
1 – 1
Grupa C
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Real Betis | 6 | 5 | 1 | 0 | 12 | 4 | 8 | 16 |
| 2 | AS Roma | 6 | 3 | 1 | 2 | 11 | 7 | 4 | 10 |
| 3 | PFK Ludogoreț Razgrad | 6 | 2 | 1 | 3 | 8 | 9 | -1 | 7 |
| 4 | HJK Helsinki | 6 | 0 | 1 | 5 | 2 | 13 | -11 | 1 |
Meciuri
8.09.2022, 19:45
PFK Ludogoreț Razgrad – AS Roma
2 – 1
8.09.2022, 19:45
HJK Helsinki – Real Betis
0 – 2
15.09.2022, 22:00
AS Roma – HJK Helsinki
3 – 0
15.09.2022, 22:00
Real Betis – PFK Ludogoreț Razgrad
3 – 2
6.10.2022, 19:45
HJK Helsinki – PFK Ludogoreț Razgrad
1 – 1
6.10.2022, 22:00
AS Roma – Real Betis
1 – 2
13.10.2022, 19:45
Real Betis – AS Roma
1 – 1
13.10.2022, 22:00
PFK Ludogoreț Razgrad – HJK Helsinki
2 – 0
27.10.2022, 19:45
PFK Ludogoreț Razgrad – Real Betis
0 – 1
27.10.2022, 22:00
HJK Helsinki – AS Roma
1 – 2
3.11.2022, 22:00
AS Roma – PFK Ludogoreț Razgrad
3 – 1
3.11.2022, 22:00
Real Betis – HJK Helsinki
3 – 0
Grupa D
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Royale Union Saint-Gilloise | 6 | 4 | 1 | 1 | 11 | 7 | 4 | 13 |
| 2 | 1. FC Union Berlin | 6 | 4 | 0 | 2 | 4 | 2 | 2 | 12 |
| 3 | SC Braga | 6 | 3 | 1 | 2 | 9 | 7 | 2 | 10 |
| 4 | Malmö FF | 6 | 0 | 0 | 6 | 3 | 11 | -8 | 0 |
Meciuri
8.09.2022, 19:45
Malmö FF – SC Braga
0 – 2
8.09.2022, 19:45
1. FC Union Berlin – Royale Union Saint-Gilloise
0 – 1
15.09.2022, 22:00
SC Braga – 1. FC Union Berlin
1 – 0
15.09.2022, 22:00
Royale Union Saint-Gilloise – Malmö FF
3 – 2
6.10.2022, 19:45
Malmö FF – 1. FC Union Berlin
0 – 1
6.10.2022, 22:00
SC Braga – Royale Union Saint-Gilloise
1 – 2
13.10.2022, 19:45
Royale Union Saint-Gilloise – SC Braga
3 – 3
13.10.2022, 22:00
1. FC Union Berlin – Malmö FF
1 – 0
27.10.2022, 19:45
1. FC Union Berlin – SC Braga
1 – 0
27.10.2022, 19:45
Malmö FF – Royale Union Saint-Gilloise
0 – 2
3.11.2022, 22:00
SC Braga – Malmö FF
2 – 1
3.11.2022, 22:00
Royale Union Saint-Gilloise – 1. FC Union Berlin
0 – 1
Grupa E
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Real Sociedad | 6 | 5 | 0 | 1 | 10 | 2 | 8 | 15 |
| 2 | Manchester United FC | 6 | 5 | 0 | 1 | 10 | 3 | 7 | 15 |
| 3 | FC Sheriff | 6 | 2 | 0 | 4 | 4 | 10 | -6 | 6 |
| 4 | AC Omonia Nicosia | 6 | 0 | 0 | 6 | 3 | 12 | -9 | 0 |
Meciuri
8.09.2022, 22:00
Manchester United FC – Real Sociedad
0 – 1
8.09.2022, 22:00
AC Omonia Nicosia – FC Sheriff
0 – 3
15.09.2022, 19:45
Real Sociedad – AC Omonia Nicosia
2 – 1
15.09.2022, 19:45
FC Sheriff – Manchester United FC
0 – 2
6.10.2022, 19:45
FC Sheriff – Real Sociedad
0 – 2
6.10.2022, 19:45
AC Omonia Nicosia – Manchester United FC
2 – 3
13.10.2022. 22:00
Manchester United FC – AC Omonia Nicosia
1 – 0
13.10.2022. 22:00
Real Sociedad – FC Sheriff
3 – 0
27.10.2022, 22:00
Manchester United FC – FC Sheriff
3 – 0
27.10.2022, 22:00
AC Omonia Nicosia – Real Sociedad
0 – 2
3.11.2022, 19:45
FC Sheriff – AC Omonia Nicosia
1 – 0
3.11.2022, 19:45
Real Sociedad – Manchester United FC
0 – 1
Grupa F
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Feyenoord Rotterdam | 6 | 2 | 2 | 2 | 13 | 9 | 4 | 8 |
| 2 | FC Midtjylland | 6 | 2 | 2 | 2 | 12 | 8 | 4 | 8 |
| 3 | SS Lazio | 6 | 2 | 2 | 2 | 9 | 11 | -2 | 8 |
| 4 | SK Sturm Graz | 6 | 2 | 2 | 2 | 4 | 10 | -6 | 8 |
Meciuri
8.09.2022, 22:00
SS Lazio – Feyenoord Rotterdam
4 – 2
8.09.2022, 22:00
SK Sturm Graz – FC Midtjylland
1 – 0
15.09.2022, 19:45
FC Midtjylland – SS Lazio
5 – 1
15.09.2022, 19:45
Feyenoord Rotterdam – SK Sturm Graz
6 – 0
6.10.2022, 19:45
SK Sturm Graz – SS Lazio
0 – 0
6.10.2022, 22:00
FC Midtjylland – Feyenoord Rotterdam
2 – 2
13.10.2022, 19:45
Feyenoord Rotterdam – FC Midtjylland
2 – 2
13.10.2022, 22:00
SS Lazio – SK Sturm Graz
2 – 2
27.10.2022, 19:45
SS Lazio – FC Midtjylland
2 – 1
27.10.2022, 22:00
SK Sturm Graz – Feyenoord Rotterdam
1 – 0
3.11.2022, 19:45
Feyenoord Rotterdam – SS Lazio
1 – 0
3.11.2022, 19:45
FC Midtjylland – SK Sturm Graz
2 – 0
Grupa G
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | SC Freiburg | 6 | 4 | 2 | 0 | 13 | 3 | 10 | 14 |
| 2 | FC Nantes | 6 | 3 | 0 | 3 | 6 | 11 | -5 | 9 |
| 3 | FK Qarabağ | 6 | 2 | 2 | 2 | 9 | 5 | 4 | 8 |
| 4 | Olympiacos FC | 6 | 0 | 2 | 4 | 2 | 11 | -9 | 2 |
Meciuri
8.09.2022, 22:00
FC Nantes – Olympiacos FC
2 – 1
8.09.2022, 22:00
SC Freiburg – FK Qarabağ
2 – 1
15.09.2022, 19:45
Olympiacos FC – SC Freiburg
0 – 3
15.09.2022, 19:45
FK Qarabağ – FC Nantes
3 – 0
6.10.2022, 22:00
Olympiacos FC – FK Qarabağ
0 – 3
6.10.2022, 22:00
SC Freiburg – FC Nantes
2 – 0
13.10.2022, 19:45
FK Qarabağ – Olympiacos FC
0 – 0
13.10.2022, 19:45
FC Nantes – SC Freiburg
0 – 4
27.10.2022, 22:00
SC Freiburg – Olympiacos FC
1 – 1
27.10.2022, 22:00
FC Nantes – FK Qarabağ
2 – 1
3.11.2022, 19:45
Olympiacos FC – FC Nantes
0 – 2
3.11.2022, 19:45
FK Qarabağ – SC Freiburg
1 – 1
Grupa H
| # | Echipa | M | V | E | I | GD | GP | Dif | P |
| 1 | Ferencváros TC | 6 | 3 | 1 | 2 | 8 | 9 | -1 | 10 |
| 2 | AS Monaco FC | 6 | 3 | 1 | 2 | 9 | 8 | 1 | 10 |
| 3 | Trabzonspor | 6 | 3 | 0 | 3 | 11 | 9 | 2 | 9 |
| 4 | Steaua Roșie Belgrad | 6 | 2 | 0 | 4 | 9 | 11 | -2 | 6 |
Meciuri
8.09.2022, 22:00
Steaua Roșie Belgrad – AS Monaco FC
0 – 1
8.09.2022, 22:00
Ferencváros TC – Trabzonspor
3 – 2
15.09.2022, 19:45
Trabzonspor – Steaua Roșie Belgrad
2 – 1
15.09.2022, 19:45
AS Monaco FC – Ferencváros TC
0 – 1
6.10.2022, 19:45
Steaua Roșie Belgrad – Ferencváros TC
4 – 1
6.10.2022, 19:45
AS Monaco FC – Trabzonspor
3 – 1
13.10.2022, 22:00
Ferencváros TC – Steaua Roșie Belgrad
2 – 1
13.10.2022, 22:00
Trabzonspor – AS Monaco FC
4 – 0
27.10.2022, 22:00
Steaua Roșie Belgrad – Trabzonspor
2 – 1
27.10.2022, 22:00
Ferencváros TC – AS Monaco FC
1 – 1
3.11.2022, 19:45
AS Monaco FC – Steaua Roșie Belgrad
4 – 1
3.11.2022, 19:45
Trabzonspor – Ferencváros TC
1 – 0