15.09.2020

FC Dinamo Kiev – AZ Alkmaar

2 – 0

15.09.2020

PAOK Salonic – Benfica

2 – 1

15.09.2020

KAA Gent – Rapid Viena

2 – 1

16.09.2020

Omonia Nicosia – Steaua Rosie Belgrad

1 – 1 d.p.
4 – 2 pen.

16.09.2020

Maccabi Tel Aviv – FC Dinamo Brest

1 – 0

16.09.2020

FK Qarabag – Molde FK

0 – 0 d.p.
5 – 6 pen.

16.09.2020

Ferencváros TC – Dinamo Zagreb

2 – 1

16.09.2020

FC Midtjylland – BSC Young Boys

3 – 0